Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy

Abstract Exosomes are nanovesicles released from most cell types including immune cells. Prior studies suggest exosomes play a role in HIV pathogenesis, but little is known about exosome cargo in relation to immune responses and oxidative stress. Here, we characterize plasma exosomes in HIV patients...

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Bibliographic Details
Main Authors: Sukrutha Chettimada, David R. Lorenz, Vikas Misra, Simon T. Dillon, R. Keith Reeves, Cordelia Manickam, Susan Morgello, Gregory D. Kirk, Shruti H. Mehta, Dana Gabuzda
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25515-4