Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes

Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes

Aberrant expression of long non-coding RNAs (lncRNA) is associated with altered DNA methylation and histone modifications during carcinogenesis. However, identifying epigenetically dysregulated lncRNAs and characterizing their functional mechanisms in different cancer subtypes are still major challe...

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Bibliographic Details
Main Authors: Hongying Zhao, Xiaoqin Liu, Lei Yu, Shihua Lin, Caiyu Zhang, Haotian Xu, Zhijun Leng, Waidong Huang, Junjie Lei, Tengyue Li, Jing Li, Fan Yang, Li Wang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
epigenetics
long non-coding RNAs
enhancer
breast cancer subtypes
prognostic biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120304054

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http://www.sciencedirect.com/science/article/pii/S2162253120304054

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