Compliance with Good Manufacturing Practice in the Assessment of Immunomodulation Potential of Clinical Grade Multipotent Mesenchymal Stromal Cells Derived from Wharton’s Jelly

Compliance with Good Manufacturing Practice in the Assessment of Immunomodulation Potential of Clinical Grade Multipotent Mesenchymal Stromal Cells Derived from Wharton’s Jelly

<b>Background</b>: The selection of assays suitable for testing the potency of clinical grade multipotent mesenchymal stromal cell (MSC)-based products and its interpretation is a challenge for both developers and regulators. Here, we present a bioprocess design for the production of Wha...

Full description

Bibliographic Details
Main Authors: Marta Grau-Vorster, Luciano Rodríguez, Anna del Mazo-Barbara, Clémentine Mirabel, Margarita Blanco, Margarita Codinach, Susana G. Gómez, Sergi Querol, Joan García-López, Joaquim Vives
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
multipotent mesenchymal stromal cell
immunomodulation
proliferation assay
cellular therapy
cell culture
good manufacturing practice
quality by design
Online Access:https://www.mdpi.com/2073-4409/8/5/484

Internet

https://www.mdpi.com/2073-4409/8/5/484

Similar Items