Heterocyclization vs Coupling Reactions: A DNA-Encoded Libraries Case

Heterocyclization vs Coupling Reactions: A DNA-Encoded Libraries Case

Aim. DNA-encoded libraries technologies (DELT) are gradually becoming an important part of standard drug discovery toolbox. DELT is looking to find its place between classic low-molecular-weight drug candidates on the one hand, and high-molecular-weight antibodies and peptides on the other hand. On...

Full description

Bibliographic Details
Main Authors: Oleksandr V. Oksiuta, Alexander E. Pashenko, Radomyr V. Smalii, Dmitry M. Volochnyuk, Serhii V. Ryabukhin
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2023-04-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
dna-encoded libraries technology
orthogonal functional groups
coupling reactions
polyfunctional building blocks
heterocyclizations
chemoinformatics
scaffold diversity
Online Access:http://ophcj.nuph.edu.ua/article/view/275133

Internet

http://ophcj.nuph.edu.ua/article/view/275133

Similar Items