Mismatch Repair Deficiency Is a Prognostic Factor Predicting Good Survival of <i>Opisthorchis viverrini</i>-Associated Cholangiocarcinoma at Early Cancer Stage

Mismatch Repair Deficiency Is a Prognostic Factor Predicting Good Survival of <i>Opisthorchis viverrini</i>-Associated Cholangiocarcinoma at Early Cancer Stage

Background: The mismatch repair (MMR) system prevents DNA mutation; therefore, deficient MMR protein (dMMR) expression causes genetic alterations and microsatellite instability (MSI). dMMR is correlated with a good outcome and treatment response in various cancers; however, the situation remains amb...

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Bibliographic Details
Main Authors: Natcha Khuntikeo, Sureerat Padthaisong, Watcharin Loilome, Poramate Klanrit, Soontaree Ratchatapusit, Anchalee Techasen, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Jarin Chindaprasirt, Prakasit Sa-ngiamwibool, Chaiwat Aphivatanasiri, Piyapharom Intarawichian, Supinda Koonmee, Piya Prajumwongs, Attapol Titapun
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
cholangiocarcinoma
<i>Opisthorchis viverrini</i>
mismatch repair proteins
microsatellite instability
prognosis
early stage
Online Access:https://www.mdpi.com/2072-6694/15/19/4831

Internet

https://www.mdpi.com/2072-6694/15/19/4831

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