The Effect of Statins on Male Reproductive Parameters: A Mechanism Involving Dysregulation of Gonadal Hormone Receptors and TRPV1

The Effect of Statins on Male Reproductive Parameters: A Mechanism Involving Dysregulation of Gonadal Hormone Receptors and TRPV1

Statins have been shown to cause diverse male reproductive function impairment, and in some cases, orchialgia. Therefore, the current study investigated the possible mechanisms through which statins may alter male reproductive parameters. Thirty adult male Wistar rats (200–250 g) were divided into t...

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Bibliographic Details
Main Authors: Temidayo S. Omolaoye, Asha C. Cyril, Rajan Radhakrishnan, Surendra Singh Rawat, Noushad Karuvantevida, Stefan S. du Plessis
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
simvastatin
rosuvastatin
male infertility
inflammation
testicular pain
sex hormone receptors
Online Access:https://www.mdpi.com/1422-0067/24/11/9221

Internet

https://www.mdpi.com/1422-0067/24/11/9221

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