Identification of hub biomarkers and immune cell infiltration characteristics of polymyositis by bioinformatics analysis

Identification of hub biomarkers and immune cell infiltration characteristics of polymyositis by bioinformatics analysis

BackgroundPolymyositis (PM) is an acquirable muscle disease with proximal muscle involvement of the extremities as the main manifestation; it is a category of idiopathic inflammatory myopathy. This study aimed to identify the key biomarkers of PM, while elucidating PM-associated immune cell infiltra...

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Bibliographic Details
Main Authors: Qi Jia, Rui-Jin-Lin Hao, Xiao-Jian Lu, Shu-Qing Sun, Jun-Jie Shao, Xing Su, Qing-Feng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
polymyositis
biomarker
LASSO algorithm
weighted gene co-expression network analysis
immune cell infiltration
single-sample gene set enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1002500/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1002500/full

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