A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism

<p>Abstract</p> <p>Background</p> <p>Opioids are the most widely used analgesics for the treatment of clinical pain. They produce their therapeutic effects by binding to μ-opioid receptors (MORs), which are 7 transmembrane domain (7TM) G-protein-coupled receptors (GPCRs...

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Bibliographic Details
Main Authors: Wentworth Sean, Pierson John, Laur Oskar, Gris Denis, Gibson Dustin G, Cheng Philip, Gauthier Josee, Gris Pavel, Nackley Andrea G, Maixner William, Diatchenko Luda
Format: Article
Language:English
Published: SAGE Publishing 2010-06-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/6/1/33