Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?

Pore-forming toxins (PFTs) form nanoscale pores across target membranes causing cell death. The pore-forming cytolysins of the RTX (repeats in toxin) family belong to a steadily increasing family of proteins characterized by having in their primary sequences a number of glycine- and aspartate-rich n...

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Bibliographic Details
Main Authors: Helena Ostolaza, David González-Bullón, Kepa B. Uribe, Cesar Martín, Jone Amuategi, Xabier Fernandez-Martínez
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/6/354