Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya.

Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya.

Malaria in pregnancy can expose the fetus to malaria-infected erythrocytes or their soluble products, thereby stimulating T and B cell immune responses to malaria blood stage antigens. We hypothesized that fetal immune priming, or malaria exposure in the absence of priming (putative tolerance), affe...

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Bibliographic Details
Main Authors: Indu Malhotra, Arlene Dent, Peter Mungai, Alex Wamachi, John H Ouma, David L Narum, Eric Muchiri, Daniel J Tisch, Christopher L King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2707618?pdf=render

Internet

http://europepmc.org/articles/PMC2707618?pdf=render

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