Senecavirus A 3C Protease Mediates Host Cell Apoptosis Late in Infection

Senecavirus A 3C Protease Mediates Host Cell Apoptosis Late in Infection

Senecavirus A (SVA), an oncolytic picornavirus used for cancer treatment in humans, has recently emerged as a vesicular disease (VD)-causing agent in swine worldwide. Notably, SVA-induced VD is indistinguishable from foot-and-mouth disease (FMD) and other high-consequence VDs of pigs. Here we invest...

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Bibliographic Details
Main Authors: Maureen H. V. Fernandes, Mayara F. Maggioli, Jaelin Otta, Lok R. Joshi, Steve Lawson, Diego G. Diel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
Senecavirus A
Seneca Valley virus
apoptosis
3C protease
virus egress
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00363/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00363/full

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