Cellular and molecular effects of PNCK, a non-canonical kinase target in renal cell carcinoma

Summary: Renal cell carcinoma (RCC) is a fatal disease when advanced. While immunotherapy and tyrosine kinase inhibitor-based combinations are associated with improved survival, the majority of patients eventually succumb to the disease. Through a comprehensive pan-cancer, pan-kinome analysis of the...

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Bibliographic Details
Main Authors: Derek J. Essegian, Valery Chavez, Floritza Bustamante, Stephan C. Schürer, Jaime R. Merchan
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222018934