Neutrophils inhibit γδ T cell functions in the imiquimod-induced mouse model of psoriasis

Neutrophils inhibit γδ T cell functions in the imiquimod-induced mouse model of psoriasis

BackgroundPsoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes. Neutrophil accumulation in the skin is a histological feature that characterizes psoriasis. However, the role of neutrophils in psoriasis onset and development remains poorly...

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Main Authors: Sara Costa, Dalila Bevilacqua, Elena Caveggion, Sara Gasperini, Elena Zenaro, Francesca Pettinella, Marta Donini, Stefano Dusi, Gabriela Constantin, Silvia Lonardi, William Vermi, Francesco De Sanctis, Stefano Ugel, Tiziana Cestari, Clare L. Abram, Clifford A. Lowell, Pamela Rodegher, Franco Tagliaro, Giampiero Girolomoni, Marco A. Cassatella, Patrizia Scapini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
neutrophils
gamma delta (gammadelta) T cells
skin inflammation
inflammatory cyotokines
immunoregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049079/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049079/full

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