PI3K-activated MSC proteomes inhibit mammary tumors via Hsp90ab1 and Myh9

PI3K-activated MSC proteomes inhibit mammary tumors via Hsp90ab1 and Myh9

Despite the advance in medications in the past decade, aggressive breast cancer such as triple-negative breast cancer is difficult to treat. Here, we examined a counter-intuitive approach to converting human bone marrow-derived mesenchymal stem cells (MSCs) into induced tumor-suppressing cells by ad...

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Bibliographic Details
Main Authors: Xun Sun, Kexin Li, Uma K. Aryal, Bai-Yan Li, Hiroki Yokota
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
breast cancer
bone metastasis
MSC
PI3K/Akt
Hsp90ab1
Myh9
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522001024

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http://www.sciencedirect.com/science/article/pii/S2372770522001024

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