Transgene excision has no impact on in vivo integration of human iPS derived neural precursors.

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors.

The derivation of induced human pluripotent stem cells (hiPS) has generated significant enthusiasm particularly for the prospects of cell-based therapy. But there are concerns about the suitability of iPS cells for in vivo applications due in part to the introduction of potentially oncogenic transcr...

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Bibliographic Details
Main Authors: Tamara Major, Jayanthi Menon, Gordon Auyeung, Frank Soldner, Dirk Hockemeyer, Rudolf Jaenisch, Viviane Tabar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3178523?pdf=render

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http://europepmc.org/articles/PMC3178523?pdf=render

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