IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers

IgG Anti-Spike Antibodies and Surrogate Neutralizing Antibody Levels Decline Faster 3 to 10 Months After BNT162b2 Vaccination Than After SARS-CoV-2 Infection in Healthcare Workers

BackgroundIgG anti-spike (S) antibodies arise after SARS-CoV-2 infection as well as vaccination. Levels of IgG anti-S are linked to neutralizing antibody titers and protection against (re)infection.MethodsWe measured IgG anti-S and surrogate neutralizing antibody kinetics against Wild Type (WT) and...

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Bibliographic Details
Main Authors: Bram Decru, Jan Van Elslande, Sophie Steels, Gijs Van Pottelbergh, Lode Godderis, Bram Van Holm, Xavier Bossuyt, Johan Van Weyenbergh, Piet Maes, Pieter Vermeersch
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVD-19 serological testing
neutralizing antibodies
vaccination
spike
IgG
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.909910/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.909910/full

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