Computational and experimental characterization of estrogenic activities of 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol

Background: As the main metabolites of ginsenosides, 20(S, R)-protopanaxadiol [PPD(S, R)] and 20(S, R)-protopanaxatriol [PPT(S, R)] are the structural basis response to a series of pharmacological effects of their parent components. Although the estrogenicity of several ginsenosides has been confirm...

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Bibliographic Details
Main Authors: Tiehua Zhang, Shuning Zhong, Ligang Hou, Yongjun Wang, XiaoJia Xing, Tianzhu Guan, Jie Zhang, Tiezhu Li
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Journal of Ginseng Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845317304025