Hypoxia-Inducible Factor-2 Alpha Regulates the Migration of Fibroblast-like Synoviocytes via Oxidative Stress-Induced CD70 Expression in Patients with Rheumatoid Arthritis

Hypoxia-Inducible Factor-2 Alpha Regulates the Migration of Fibroblast-like Synoviocytes via Oxidative Stress-Induced CD70 Expression in Patients with Rheumatoid Arthritis

This study aimed to examine the role of CD70, which is highly expressed on fibroblast-like synoviocytes (FLS), in rheumatoid arthritis (RA) patients. FLS isolated from RA (<i>n</i> = 14) and osteoarthritis (OA, <i>n</i> = 4) patients were stimulated with recombinant interleuk...

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Bibliographic Details
Main Authors: Su-Jin Yoo, Ha-Reum Lee, Jinhyun Kim, In Seol Yoo, Chan Keol Park, Seong Wook Kang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
reactive oxygen species
cytokines
antioxidants
synovial fluid
Online Access:https://www.mdpi.com/1422-0067/23/4/2342

Internet

https://www.mdpi.com/1422-0067/23/4/2342

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