Gelatin-coated silicon oxide nanoparticles encapsulated recombinant human secretory leukocyte protease inhibitor (rhSLPI) reduced cardiac cell death against an in vitro simulated ischaemia/reperfusion injury

Gelatin-coated silicon oxide nanoparticles encapsulated recombinant human secretory leukocyte protease inhibitor (rhSLPI) reduced cardiac cell death against an in vitro simulated ischaemia/reperfusion injury

Ischemic Heart Disease (IHD) is the main global cause of death. Previous studies indicated that recombinant human secretory leukocyte protease inhibitor (rhSLPI) exhibits a cardioprotective effect against myocardial ischaemia/reperfusion (I/R) injury. However, SLPI has a short half-life in vivo due...

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Bibliographic Details
Main Authors: Faprathan Pikwong, Chayanisa Phutiyothin, Wannapat Chouyratchakarn, Phornsawat Baipaywad, Podsawee Mongkolpathumrat, Sarawut Kumphune
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Secretory leukocyte protease inhibitor (SLPI)
Gelatin-covered silica nanoparticles
Nanoparticles
Ischaemia and reperfusion (I/R) injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023073589

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http://www.sciencedirect.com/science/article/pii/S2405844023073589

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