Impact of estrogen on IgG glycosylation and serum protein glycosylation in a murine model of healthy postmenopause

Impact of estrogen on IgG glycosylation and serum protein glycosylation in a murine model of healthy postmenopause

IntroductionThe glycosylation of immunoglobulin (Ig) G regulates IgG interaction capability with Fc gamma receptors found in all immune cells. In pathogenic conditions, estrogen can impact IgG levels and glycosylation. Following menopause, when estrogen levels decline affecting the immune system and...

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Bibliographic Details
Main Authors: Priti Gupta, Tibor Sághy, Jauquline Nordqvist, Jonas Nilsson, Hans Carlsten, Karin Horkeby, Petra Henning, Cecilia Engdahl
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
IgG
estrogen
IgG-glycosylation
sialylation
sialic acid
animal
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1243942/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1243942/full

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