Altered Gut Microbiome and Fecal Immune Phenotype in Early Preterm Infants With Leaky Gut

Altered Gut Microbiome and Fecal Immune Phenotype in Early Preterm Infants With Leaky Gut

Intestinal barrier immaturity, or “leaky gut”, is the proximate cause of susceptibility to necrotizing enterocolitis in preterm neonates. Exacerbated intestinal immune responses, gut microbiota dysbiosis, and heightened barrier injury are considered primary triggers of aberrant intestinal maturation...

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Bibliographic Details
Main Authors: Jose M. Lemme-Dumit, Yang Song, Hnin Wai Lwin, Claudia Hernandez-Chavez, Sripriya Sundararajan, Rose M. Viscardi, Jacques Ravel, Marcela F. Pasetti, Bing Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
preterm infants
gut microbiome
fecal cytokines
local immune phenotype
intestinal barrier maturation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.815046/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.815046/full

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