INTRAHIPPOCAMPAL ADMINISTRATION OF IBOTENIC ACID INDUCED CHOLINERGIC DYSFUNCTION via NR2A/NR2B EXPRESSION: IMPLICATIONS OF RESVERATROL AGAINST ALZHEIMER DISEASE PATHOPHYSIOLOGY

INTRAHIPPOCAMPAL ADMINISTRATION OF IBOTENIC ACID INDUCED CHOLINERGIC DYSFUNCTION via NR2A/NR2B EXPRESSION: IMPLICATIONS OF RESVERATROL AGAINST ALZHEIMER DISEASE PATHOPHYSIOLOGY

Although several drugs revealed moderate amelioration of symptoms, none of them have sufficient potency to prevent or reverse the progression towards Alzheimer’s disease (AD) pathology. Resveratrol (RSV), a polyphenolic compound has shown an outstanding therapeutic effect on a broad spectrum of dise...

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Bibliographic Details
Main Authors: Chennakesavan eKarthick, Sabapathy ePeriyasamy, Kesavan Swaminathan Jayachandran, Muthuswamy eAnusuyadevi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Hippocampus
Ibotenic Acid
Memory
resveratrol
Alzheimer’s disease
acetylcholine receptors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00028/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00028/full

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