RPLP1 restricts HIV-1 transcription by disrupting C/EBPβ binding to the LTR

Abstract Long-term non-progressors (LTNPs) of HIV-1 infection may provide important insights into mechanisms involved in viral control and pathogenesis. Here, our results suggest that the ribosomal protein lateral stalk subunit P1 (RPLP1) is expressed at higher levels in LTNPs compared to regular pr...

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Bibliographic Details
Main Authors: Weijing Yang, Hong Wang, Zhaolong Li, Lihua Zhang, Jianhui Liu, Frank Kirchhoff, Chen Huan, Wenyan Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49622-1