Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities

Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities

Myeloid neoplasms (MN) are heterogeneous clonal disorders arising from the expansion of hematopoietic stem and progenitor cells. In parallel with genetic and epigenetic dynamics, the immune system plays a critical role in modulating tumorigenesis, evolution and therapeutic resistance at the various...

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Bibliographic Details
Main Authors: Chiara Caprioli, Iman Nazari, Sara Milovanovic, Pier Giuseppe Pelicci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
single-cell sequencing
myelodysplastic syndromes
acute myeloid leukemia
clonal hematopoiesis
immunotherapies
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.796477/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.796477/full

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