C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors

The skin is the first line of defense to cutaneous microbes and viruses, and epidermal keratinocytes play a critical role in preventing infection by viruses and pathogens through activation of the type I interferon (IFN) response. Using RNAseq analysis, here we report that the conditional deletion o...

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Bibliographic Details
Main Authors: John S. House, Sophia Gray, Jennifer R. Owen, Dereje D. Jima, Robert C. Smart, Jonathan R. Hall
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259231162192