Pharmacokinetics of a microdosed cocktail of three direct oral anticoagulants in children with congenital heart defects: study protocol for a single-centre clinical trial (DOAC-Child)
Introduction Direct oral anticoagulants (DOACs) are direct inhibitors of coagulation factor Xa and are frequently used in adults for different indications such as deep vein thrombosis or non-valvular atrial fibrillation. Paediatric patients might benefit as well from DOACs because the simplicity and...
Main Authors: | Matthias Gorenflo, Victoria C. Ziesenitz, Gerd Mikus, Simon A Hermann, Kristine Chobanyan-Jürgens |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2023-12-01
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Series: | BMJ Paediatrics Open |
Online Access: | https://bmjpaedsopen.bmj.com/content/7/1/e001662.full |
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