OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis via regulating the arachidonic acid metabolism

OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis via regulating the arachidonic acid metabolism

BackgroundOncoprotein-Induced Transcript 3 Protein (OIT3) was identified as a liver-specific gene with abnormal expression in hepatocellular carcinoma (HCC). Herein, we aimed to examine the function and specific mechanism of OIT3 in HCC.MethodsBioinformatic analyses and tissue microarray via immunoh...

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Bibliographic Details
Main Authors: Jie Wen, Abudureyimujiang Aili, Yao Xue Yan, YuLin Lai, Shaoqing Niu, Shasha He, Xiaokai Zhang, Guixiong Zhang, Jiaping Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
HCC
OIT3
ferroptosis
arachidonic acid
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.977348/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.977348/full

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