Association of CSF and PET markers of neurodegeneration with electroclinical progression in Lafora disease

Association of CSF and PET markers of neurodegeneration with electroclinical progression in Lafora disease

PurposeTo evaluate the electro-clinical features in association with laboratory and instrumental correlates of neurodegeneration to detect the progression of Lafora disease (LD).MethodsWe investigated the electro-clinical longitudinal data and CSF Aβ42, p-tau181 and t-tauAg, amyloid, and 18F-FDG PET...

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Bibliographic Details
Main Authors: Giuseppe d'Orsi, Andrea Farolfi, Lorenzo Muccioli, Orazio Palumbo, Pietro Palumbo, Sergio Modoni, Vincenzo Allegri, Valentina Garibotto, Maria Teresa Di Claudio, Ester Di Muro, Mario Benvenuto, Francesca Bisulli, Massimo Carella
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neurology
Subjects:
follow-up
Lafora disease
electro-clinical features
amyloid biomarkers
neurodegenerative biomarkers
progressive myoclonic epilepsy
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1202971/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1202971/full

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