Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers

Beta-catenin (i.e., canonical Wnt) signaling controls CNS angiogenesis and the blood-brain and blood-retina barriers. To explore the role of the Discs large/membrane-associated guanylate kinase (Dlg/MAGUK) family of scaffolding proteins in beta-catenin signaling, we studied vascular endothelial cell...

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Bibliographic Details
Main Authors: Chris Cho, Yanshu Wang, Philip M Smallwood, John Williams, Jeremy Nathans
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/45542