Role of radiotherapy in treatment of extramedullary relapse following total marrow and lymphoid irradiation in high-risk and/or relapsed/refractory acute leukemia

Role of radiotherapy in treatment of extramedullary relapse following total marrow and lymphoid irradiation in high-risk and/or relapsed/refractory acute leukemia

BackgroundTotal Marrow and Lymphoid Irradiation (TMLI) is a promising component of the preparative regimen for hematopoietic cell transplantation in patients with high-risk acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL). Extramedullary (EM) relapse after TMLI is comparable to TBI and...

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Bibliographic Details
Main Authors: Colton Ladbury, Hemal Semwal, Daniel Hong, Dongyun Yang, Claire Hao, Chunhui Han, An Liu, Guido Marcucci, Joseph Rosenthal, Susanta Hui, Amandeep Salhotra, Haris Ali, Ryotaro Nakamura, Anthony Stein, Monzr Al Malki, Jeffrey Y. C. Wong, Savita Dandapani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
TMLI
ALL
AML
leukemia
radiation
relapse
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1017355/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1017355/full

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