Secretome Analyses Identify FKBP4 as a <i>GBA1</i>-Associated Protein in CSF and iPS Cells from Parkinson’s Disease Patients with <i>GBA1</i> Mutations

Secretome Analyses Identify FKBP4 as a <i>GBA1</i>-Associated Protein in CSF and iPS Cells from Parkinson’s Disease Patients with <i>GBA1</i> Mutations

Mutations in the <i>GBA1</i> gene increase the risk of developing Parkinson’s disease (PD). However, most carriers of <i>GBA1</i> mutations do not develop PD throughout their lives. The mechanisms of how <i>GBA1</i> mutations contribute to PD pathogenesis remain u...

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Bibliographic Details
Main Authors: Rika Kojima, Wojciech Paslawski, Guochang Lyu, Ernest Arenas, Xiaoqun Zhang, Per Svenningsson
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
<i>GBA1</i>
secretome
cerebrospinal fluid
human-induced pluripotent stem cells (hiPSCs)
FKBP4
Online Access:https://www.mdpi.com/1422-0067/25/1/683

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https://www.mdpi.com/1422-0067/25/1/683

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