Identifying novel SMYD3 interactors on the trail of cancer hallmarks

Identifying novel SMYD3 interactors on the trail of cancer hallmarks

SMYD3 overexpression in several human cancers highlights its crucial role in carcinogenesis. Nonetheless, SMYD3 specific activity in cancer development and progression is currently under debate. Taking advantage of a library of rare tripeptides, which we first tested for their in vitro binding affin...

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Bibliographic Details
Main Authors: Candida Fasano, Martina Lepore Signorile, Katia De Marco, Giovanna Forte, Paola Sanese, Valentina Grossi, Cristiano Simone
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Gastrointestinal cancer cell lines
Hallmarks of cancer
In silico tripeptide screening
SMYD3
SMYD3 interactome
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702200112X

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http://www.sciencedirect.com/science/article/pii/S200103702200112X

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