Epistatic relationships reveal the functional organization of yeast transcription factors

Epistatic relationships reveal the functional organization of yeast transcription factors

The regulation of gene expression is, in large part, mediated by interplay between the general transcription factors (GTFs) that function to bring about the expression of many genes and site‐specific DNA‐binding transcription factors (STFs). Here, quantitative genetic profiling using the epistatic m...

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Bibliographic Details
Main Authors: Jiashun Zheng, Joris J Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank Holstege, Hao Li, Nevan J Krogan
Format: Article
Language:English
Published: Springer Nature 2010-01-01
Series:Molecular Systems Biology
Subjects:
genetic interaction
regulatory network
transcription factor
transcription regulation
Online Access:https://doi.org/10.1038/msb.2010.77

Internet

https://doi.org/10.1038/msb.2010.77

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