Epistatic relationships reveal the functional organization of yeast transcription factors
Abstract The regulation of gene expression is, in large part, mediated by interplay between the general transcription factors (GTFs) that function to bring about the expression of many genes and site‐specific DNA‐binding transcription factors (STFs). Here, quantitative genetic profiling using the ep...
Main Authors: | Jiashun Zheng, Joris J Benschop, Michael Shales, Patrick Kemmeren, Jack Greenblatt, Gerard Cagney, Frank Holstege, Hao Li, Nevan J Krogan |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-10-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.77 |
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