Standardizing HER2 immunohistochemistry assessment: calibration of color and intensity variation in whole slide imaging caused by staining and scanning

Abstract In the evaluation of human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) — one of the standard biomarkers for breast cancer— visual assessment is laborious and subjective. Image analysis using whole slide image (WSI) could produce more consistent results; however, col...

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Bibliographic Details
Main Authors: Chie Ohnishi, Takashi Ohnishi, Peter Ntiamoah, Dara S. Ross, Masahiro Yamaguchi, Yukako Yagi
Format: Article
Language:English
Published: SpringerOpen 2023-09-01
Series:Applied Microscopy
Subjects:
Online Access:https://doi.org/10.1186/s42649-023-00091-8