In Vitro Study of Endothelial Cell Morphology and Gene Expression in Response to Wall Shear Stress Induced by Arterial Stenosis

In Vitro Study of Endothelial Cell Morphology and Gene Expression in Response to Wall Shear Stress Induced by Arterial Stenosis

Objectives: We examined the correlation between changes in hemodynamic characteristics induced by arterial stenosis and vascular endothelial cell (EC) morphology and gene expression in straight silicone arteries.Materials and methods: Transparent silicone straight artery models with four degrees of...

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Bibliographic Details
Main Authors: Lizhong Mu, Xiaolong Liu, Mengmeng Liu, Lili Long, Qingzhuo Chi, Ying He, Yue Pan, Changjin Ji, Ge Gao, Xiaona Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
vascular stenosis
silicone-endothelial cell model
wall shear stress
inflammatory factor
EC morphology
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.854109/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.854109/full

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