Engineering of Microbial Substrate Promiscuous CYP105A5 for Improving the Flavonoid Hydroxylation

Bacterial cytochrome P450 (CYP) enzymes are versatile biocatalysts that are responsible for the biotransformation of diverse endogenous substances. CYP105A5 from <i>Streptomyces</i> sp. showed substrate flexibility with different flavonoids and was able to catalyze O-demethylation of bio...

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Bibliographic Details
Main Authors: Pradeep Subedi, Jong Kook Park, Tae-Jin Oh
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/12/10/1157