Thrombospondin 1 Mediates Autophagy Upon Inhibition of the Rho-Associated Protein Kinase Inhibitor

Thrombospondin 1 Mediates Autophagy Upon Inhibition of the Rho-Associated Protein Kinase Inhibitor

Age-related macular degeneration (AMD) is a degenerative eye disease leading to central vision loss and is characterized by dysregulated autophagy of the retinal pigment epithelium (RPE) layer. Recent studies have suggested that rho-associated protein kinase (ROCK) inhibitors may enhance autophagy i...

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Bibliographic Details
Main Authors: Kirk Patrick Carreon Catral, Choi-Yee Tse, Wei-Ying Yang, Choi-Ying Ling, Oi-Lam Kwok, Kit-Ying Choy, Da-Qian Lu, Jing-Fang Bian, Thomas Chuen Lam, Dennis Yan-Yin Tse, Samantha Sze-Wan Shan
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
autophagy
Thrombospondin-1
ROCK inhibitor
AMD
signaling pathway
Online Access:https://www.mdpi.com/2073-4409/13/22/1907

Internet

https://www.mdpi.com/2073-4409/13/22/1907

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