Fine-tuning of highly bright benzo[c,d]indole-oxazolopyridine cyanine dye for nucleolar RNA imaging in living cells

Fine-tuning of highly bright benzo[c,d]indole-oxazolopyridine cyanine dye for nucleolar RNA imaging in living cells

Here we report on fine-tuning of highly bright fluorogenic cyanine dye, benzo[c,d]indole-oxazolo[5,4-c]pyridine (BIOP: λem = 570 nm, Φfree = 0.00038, Φbound = 0.52), recently developed by our group for nucleolar RNA imaging in living cells. We tuned an emission maximum to the longer wavelength by re...

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Bibliographic Details
Main Authors: Nao Togashi, Masaaki Nagaoka, Kei Higuchi, Yukina Yoshino, Yawen Wu, Yusuke Sato, Seiichi Nishizawa
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Talanta Open
Subjects:
Small molecule
Cyanine dye
RNA
Imaging
Live cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831924000225

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http://www.sciencedirect.com/science/article/pii/S2666831924000225

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