Parthenolide alleviates cognitive dysfunction and neurotoxicity via regulation of AMPK/GSK3β(Ser9)/Nrf2 signaling pathway

Parthenolide alleviates cognitive dysfunction and neurotoxicity via regulation of AMPK/GSK3β(Ser9)/Nrf2 signaling pathway

Alzheimer's disease (AD) stands as the predominant age-related neurodegenerative disorder, for which efficacious treatment remains elusive. An auspicious avenue for this disease lies in natural compounds sourced from tranditional medicine and plant origins. Parthenolide (PTN) is a natural produ...

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Bibliographic Details
Main Authors: Jinfeng Sun, Liwei Li, Li Xiong, Fan Chen, Lingyu She, Hao Tang, Yuqing Zeng, Ying Duan, Luyao Li, Wei Wang, Gao Li, Xia Zhao, Guang Liang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer’s disease
Parthenolide
Cell apoptosis
Cognitive deficits
AMPK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017079

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http://www.sciencedirect.com/science/article/pii/S0753332223017079

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