Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ

Summary: The transcription factor Sox21 is expressed in the epithelium of developing teeth. The present study aimed to determine the role of Sox21 in tooth development. We found that disruption of Sox21 caused severe enamel hypoplasia, regional osteoporosis, and ectopic hair formation in the gingiva...

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Bibliographic Details
Main Authors: Kan Saito, Frederic Michon, Aya Yamada, Hiroyuki Inuzuka, Satoko Yamaguchi, Emiko Fukumoto, Keigo Yoshizaki, Takashi Nakamura, Makiko Arakaki, Yuta Chiba, Masaki Ishikawa, Hideyuki Okano, Irma Thesleff, Satoshi Fukumoto
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Rodent Dentistry
Developmental Genetics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305162

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http://www.sciencedirect.com/science/article/pii/S2589004220305162

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