Interactions between the protein barnase and co-solutes studied by NMR

Abstract Protein solubility and stability depend on the co-solutes present. There is little theoretical basis for selection of suitable co-solutes. Some guidance is provided by the Hofmeister series, an empirical ordering of anions according to their effect on solubility and stability; and by osmoly...

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Bibliographic Details
Main Authors: Clare R. Trevitt, D. R. Yashwanth Kumar, Nicholas J. Fowler, Mike P. Williamson
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01127-0