Hippocampal Long-Term Depression in the Presence of Calcium-Permeable AMPA Receptors

The GluA2 subunit of AMPA glutamate receptors (AMPARs) has been shown to be critical for the expression of NMDA receptor (NMDAR)-dependent long-term depression (LTD). However, in young GluA2 knockout (KO) mice, this form of LTD can still be induced in the hippocampus, suggesting that LTD mechanisms...

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Bibliographic Details
Main Authors: Feng Cao, Zikai Zhou, Sammy Cai, Wei Xie, Zhengping Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2018.00041/full