Determination of residual solvents in synthetic intermediate of Selexipag by headspace gas chromatograhy

In order to better control the quality of Selexipag products and ensure drug safety,headspace gas chromatography is established to detect the amount of solvent remaining in the synthesis of Selexipag intermediates 4-\ pyrazin -2-yl) (isopropyl) amino\]-1-butanol (S5) and N-(2-chloroacetyl) methyl su...

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Bibliographic Details
Main Authors: Haijuan QI, Haoliang CUI, Xiaoqing DENG, Hongpeng WANG, Shuangshuang GAO, Jing HA
Format: Article
Language:zho
Published: Hebei University of Science and Technology 2019-06-01
Series:Journal of Hebei University of Science and Technology
Subjects:
Online Access:http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201903005&flag=1&journal_