Mutually exclusive expression of virulence genes by malaria parasites is regulated independently of antigen production.
The primary virulence determinant of Plasmodium falciparum malaria parasite-infected cells is a family of heterogeneous surface receptors collectively referred to as PfEMP1. These proteins are encoded by a large, polymorphic gene family called var. The family contains approximately 60 individual gen...
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-03-01
|
| Series: | PLoS Pathogens |
| Online Access: | http://dx.doi.org/10.1371/journal.ppat.0020022 |