Transcription-based prediction of response to IFNbeta using supervised computational methods.

Changes in cellular functions in response to drug therapy are mediated by specific transcriptional profiles resulting from the induction or repression in the activity of a number of genes, thereby modifying the preexisting gene activity pattern of the drug-targeted cell(s). Recombinant human interfe...

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Bibliographic Details
Main Authors: Sergio E Baranzini, Parvin Mousavi, Jordi Rio, Stacy J Caillier, Althea Stillman, Pablo Villoslada, Matthew M Wyatt, Manuel Comabella, Larry D Greller, Roland Somogyi, Xavier Montalban, Jorge R Oksenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0030002