Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants

Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants

Near full genome sequencing (NFGS) of HIV-1 is required to assess the genetic composition of HIV-1 strains comprehensively. Population-wide, it enables a determination of the heterogeneity of HIV-1 and the emergence of novel/recombinant strains, while for each individual it constitutes a diagnostic...

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Bibliographic Details
Main Authors: Andrew N. Banin, Michael Tuen, Jude S. Bimela, Marcel Tongo, Paul Zappile, Alireza Khodadadi-Jamayran, Aubin J. Nanfack, Josephine Meli, Xiaohong Wang, Dora Mbanya, Jeanne Ngogang, Adriana Heguy, Phillipe N. Nyambi, Charles Fokunang, Ralf Duerr
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Viruses
Subjects:
Near full genome amplification and sequencing
HIV-1 group M subtype-independent approach
rational primer design
single-genome amplification (SGA)
third-generation sequencing (TGS)
bulk sequencing and cloning
Online Access:https://www.mdpi.com/1999-4915/11/4/317

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https://www.mdpi.com/1999-4915/11/4/317

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