Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice

Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice

Abstract Hematopoietic cell transplantation (HCT) treats many blood conditions but remains underused due to complications such as graft‐versus‐host disease (GvHD). In GvHD, donor immune cells attack the patient, requiring powerful immunosuppressive drugs like glucocorticoids (GCs) to prevent death....

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Bibliographic Details
Main Authors: Erika S Varady, L Angel Ayala, Pauline U Nguyen, Vanessa M Scarfone, Alborz Karimzadeh, Cuiwen Zhou, Xiyu Chen, Scott A Greilach, Craig M Walsh, Matthew A Inlay
Format: Article
Language:English
Published: Springer Nature 2023-09-01
Series:EMBO Molecular Medicine
Subjects:
allogeneic transplantation
blood and marrow transplantation
glucocorticoids
graft‐versus‐host disease
hematopoietic stem cells
Online Access:https://doi.org/10.15252/emmm.202317748

Internet

https://doi.org/10.15252/emmm.202317748

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