A bipartite, low-affinity roadblock domain-containing GAP complex regulates bacterial front-rear polarity.

The Ras-like GTPase MglA is a key regulator of front-rear polarity in the rod-shaped Myxococcus xanthus cells. MglA-GTP localizes to the leading cell pole and stimulates assembly of the two machineries for type IV pili-dependent motility and gliding motility. MglA-GTP localization is spatially const...

Full description

Bibliographic Details
Main Authors: Dobromir Szadkowski, Luís António Menezes Carreira, Lotte Søgaard-Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010384