Thalamocortical control of propofol phase-amplitude coupling.

Thalamocortical control of propofol phase-amplitude coupling.

The anesthetic propofol elicits many different spectral properties on the EEG, including alpha oscillations (8-12 Hz), Slow Wave Oscillations (SWO, 0.1-1.5 Hz), and dose-dependent phase-amplitude coupling (PAC) between alpha and SWO. Propofol is known to increase GABAA inhibition and decrease H-curr...

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Bibliographic Details
Main Authors: Austin E Soplata, Michelle M McCarthy, Jason Sherfey, Shane Lee, Patrick L Purdon, Emery N Brown, Nancy Kopell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5739502?pdf=render

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http://europepmc.org/articles/PMC5739502?pdf=render

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